ZIOPHARM is actively seeking to in-license cancer drugs as well as to out-license its programs and to establish novel corporate partnerships to move the company forward in the currently changed market environment worldwide.

We are looking throughout the world, including the emerging growth markets of China, India, Russia, Korea, and Brazil, and we actively encourage partnering or business development managers to contact us with in-and out-licensing proposals. You will find ZIOPHARM to be extremely responsive to your inquiries.

Our business model is based on developing licensed drugs. ZIOPHARM's value is based on the clinical quality of the drugs we develop, the experienced development team and timelines to approval and establishment of corporate partnerships. We are professionally, ethically and financially motivated to move drugs through clinical trial phases as efficiently as possible.

We are closely aligned with the clinical and drug development strategies embodied in the early drafts of the FDA's Critical Path Initiative, designed to streamline drug development. It sets forth a clear willingness and openness to considering new ways of approaching trial design and endpoint selection, including the use of biomarkers as surrogate endpoints and computer modeling and simulation to streamline the clinical trial process.

Each product entering the ZIOPHARM pipeline will be evaluated carefully to determine the best enrichment strategy to address a rapidly changing healthcare marketplace worldwide. We will analyze clinical trial results using the extremely vigorous standards of current clinical trial practice.

Our clinical development programs are designed so efficacy of a specific agent can be quickly determined in an oncology population with unmet medical needs. Each product candidate should also meet the criteria of having the longer term potential value to a wide variety of cancer patients.

We are flexible with regard to financial arrangements. We know there are certain norms in the business, and we use those as the beginning point to create sensible deals that provide ample opportunity for risk-reward sharing. You will find us very approachable and open to all formats of deal structure. We seek excellent products and happy partners.