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Date Event
March 30 - April 4, 2012

AACR 103rd Annual Meeting 2012

location:
location: Chicago, IL

Click here for the “Norton-Simon Modeling for the Optimization of Dose and Schedule of Palifosfamide in Breast Cancer” poster
(923 KB Download)

Click here for the “Combination of Intratumoral Regulated IL-12 Gene Delivery and Systemic Chemotherapy with Palifosfamide (IPM-Tris) Enhances Anti-Tumor Effects in Breast Cancer (4T1) Mode” poster
(726 KB Download)

Click here for the “Combined Direct Intratumoral Adenoviral Delivery and Production of RheoSwitch®-Regulated mIL-12 and mIFNα Enhances Antitumor Activity in Lung and Breast Cancer Models” poster
(1.08 MB Download)

Click here for the “Targeting EVI1-overexpressing AML with Darinaparsin” poster
(1.06 MB Download)


November 12-16, 2011

AACR-NCI-EORTC
International Conference: Molecular Targets and Cancer Therapeutics

location:
San Francisco, CA

Click here for the “Darinaparsin (Z101) Inhibits Prostate Cancer Stem Cells via Inhibition of Hedgehog Signaling.” poster
(1.23 MB Download)

Click here for the “Multicenter Phase Ib Study of the Safety and Efficacy of Palifosfamide Plus Carboplatin/Etoposide (PaCE) in Patients with Small Cell Lung Cancer or Other Selected Cancers” poster
(952 KB Download)

Click here for the “Darinaparsin is an anti-solid tumor cytotoxin in vivo” poster
(6.5 MB Download)

Click here for the “Darinaparsin sensitizes solid tumors, but not normal tissues, to radiation” poster
(840 KB Download)

June 3-7, 2011
ASCO
2011 Annual Meeting of the American Society of Clinical Oncology

location:
Chicago, IL

Click here for the “Immunotherapy of Advanced Melanoma by Intra-Tumoral Injections of Autologous, Purified Dendritic Cells Transduced with Gene Construct of Interleukin-12, with Dose-Dependent Expression Under the Control of an Oral Activator Ligand" poster
(745 KB Download)
May 18-21, 2011
ASGCT
2011 Annual Meeting of the American Society of Gene and Cell Therapy

location:
Seattle, WA

Click here for the “Local and Systemic Anti-Tumor Immunity is Induced by Rheoswitch Regulated IL-12 Production after Intra-Tumoral Injection of Adenovirus Vector as well as Vector-Transduced Dendritic Cells” poster (1.07 MB Download)

Click here for the “RheoSwitch-Mediated Regulation of IL-12 Protein Delivered Using an Adenoviral Vector Results in Anti-Tumor Effects Across a Spectrum of Tumor Types” poster (872 KB Download)

November 16-19, 2010
EORTC-NCI-AACR
International Symposium on Molecular Targets and Cancer Therapeutics

location:
Berlin, Germany

Click here for the "Darinaparsin (ZIO-101) is a novel cytotoxic and radiosensitizing anti-cancer agent" poster (237 KB Download)

Click here for the "Darinaparsin (ZIO-101) is a novel cytotoxic and radiosensitizing anti-cancer agent" abstract (7.60 KB Download)

April 17-21, 2010
AACR 101st Annual Meeting 2010

location:
Washington, DC

Click here for the "Evaluation of RNA-stress granules formation as an indicator of response to Darinaparsin in cancer cell lines" poster (325 KB Download)

November 15-19, 2009
AACR-NCI-EORTC International Conference

location:
Boston, MA

Click here for the "The Role of Cystine Transport in Darinaparsin-induced cell death" poster (503 KB Download)

November 5-7, 2009
15th Annual Connective Tissue Oncology Society (CTOS) Meeting

location:
Miami Beach, FL

Click here for the "A Phase II Randomized Controlled Trial of Palifosfamide Plus Doxorubicin vs. Doxorubicin in Patients with Soft Tissue Sarcoma (PICASSO)" poster (248 KB Download)

May 29-June 2, 2009
45th Annual American Society of Clinical Oncology (ASCO) Meeting

location:
Orlando, FL

Click here for the "A Phase I Study of Palifosfamide in Combination with Doxorubicin: Safety and Preliminary Efficacy" poster (611 KB Download)

Click here for the "Novel Organic Arsenic Molecule Darinaparsin: Development of IV and Oral Forms" presentation (5 MB Download)

Click here for the "Indibulin, a Novel Tubulin Targeting-Agent, in Combination with Capecitabine, is Suitable for Mathematically-Optimized Dose-Scheduling" poster (147 KB Download)
December 6-9, 2008
50th ASH Annual Meeting & Exposition

location:
San Francisco, CA

Click here for the "A Phase II Trial of Darinaparsin in Advanced Lymphomas: Report on Safety and Activity" poster (608 KB Download)
November 13-15, 2008
14th Annual CTOS Meeting

location:
London, England

Click here for the "A Study of Palifosfamide in Combination with Doxorubicin: Safety and Preliminary Efficacy" poster (1,211 KB Download)
October 21-24, 2008
20th EORTC-NCI-AACR symposium on “Molecular targets and Cancer Therapeutics

location:
Geneva, Switzerland

Click here for the "A novel arsenical, Darinaparsin, induces apoptosis in As2O3-resistant and MRP1/ABCC1-overexpressing cell lines" poster (656 KB Download)
July 20-23, 2008
AACR

location:
Monterey, CA

Click here for the "A Novel Oral Tubulin Inhibitor; Safety and Preliminary Efficacy of Two Phase I Studies with Indibulin" poster (1370 KB Download)
April 12-17, 2008
AACR

location:
San Diego, CA

Click here for the "Phase II Trial of Darinaparsin (ZIO-101) in Leukemias and Lymphomas" poster (204 KB Download)

Click here for the "Oral Availability and Drug Combination Activity of Palifosfamide Tris (ZIO-201) in Preclinical Studies" poster (182 KB Download)
March 20-22, 2008
6th International Symposium on Targeted Anticancer Thearapies (TAT)

location:
Bethesda, MD

Click here for the "Safety and PET Evaluation of Patients Treated with Oral Indibulin, a Novel Microtubule Disrupting Agent" poster (287 KB Download)
November 1-3, 2007
CTOS

location:
Seattle, WA

Click here for the "ZIO-201: A Bi-functional DNA Alkylator in Advanced Sarcomas" poster (207 KB Download)
October 22, 2007
AACR/NCI/EORTC Conference

location:
San Francisco, CA

Click here for the "Indibulin (ZIO-301): An Orally Active Tubulin Polymerization Inhibitor with a Unique Molecular Mechanism of Action" poster (1260 KB Download)

Click here for the "Translation of Indibulin (ZIO-301) Preclinical Antiangiogenic and Antimetastatic Activity to the Clinic" poster (838 KB Download)
September 23-27, 2007
ECCO 14 The European Cancer Conference

location:
Barcelona, Spain

Click here for the "A Novel Organic Arsenic, Darinaparsin (ZIO-101): Experience in Hematological Malignancies" poster (306 KB Download)

Click here for the "Phase II Study of ZIO-201 in Advanced Sarcoma" poster (379 KB Download)
July 5-8, 2007
ESMO

location:
Lugano, Switzerland

Click here for the "Phase I/II Study of ZIO-201 in Advanced Sarcoma" poster (300 KB Download)
June 25-30, 2007
XIth International Myeloma Workshop

location:
Kos, Greece

Click here for the "S-dimethylarsinoglutathione (ZIO-101): A novel arsenical with activity in myeloma" poster (112 KB Download)

Click here for the "ZIO-101 (S-dimethylarsino-glutathione): Phase I/II Trials in Advanced/Progressive Multiple Myeloma" poster (139 KB Download)
June 1-5, 2007
ASCO

location:
Chicago, IL

Click here for the "ZIO-101 (S-dimethylarsino-glutathione): Phase 1/2 Trials in Advanced/Progressive Multiple Myeloma" poster (1,170 KB Download)

Click here for the "Organic Arsenic in Advanced Cancers: Preliminary Phase 1 Results of ZIO-101 (S-dimethylarsino-glutathione)" poster (496 KB Download)

Click here for the "Phase 1 and Pharmacological Study of Orally Administered Indibulin in Advanced Solid Tumors" poster (404 KB Download)
April 14-18, 2007
AACR

location:
Los Angeles

Click here for the "ZIO-101 (S-dimethyl-arsino-glutathione): An Oral Multi-Targeted Anti-Cancer Drug with Anti-Angiogenic Activity" poster (299 KB Download)

Click here for the "S-dimethylarsinoglutathione (ZIO-101): A novel organic arsenic with a unique gene expression profile in myeloma" poster (392 KB Download)

Click here for the "ZIO-201 (Isophosphoramide Mustard; IPM): An Orally Active Anti-Cancer Agent" poster (131 KB Download)

Click here for the "Indibulin (ZIO-301): A Novel Tubulin Polymerization Inhibitor has Potent Anti-Tumor Activity and a Distinct Tubulin Binding Site" poster (411 KB Download)
March 21-25, 2007
XXXI World Congress of the International Society of Hematology

location:
Punta del Este, Uruguay

Click here for the "ZIO-201 (Isophosphoramide Mustard-Lysine): A New Alkylator for Lymphoma Active in Ifosfamide (IFOS)-Resistant Cancers" poster (188 KB Download)
February 8-12, 2007
BMT Tandem Meetings

location:
Keystone, CO

Click here for the "Use of a Novel Organic Arsenic (ZIO-101) After Autotransplants from Multiple Myeloma" poster (402 KB Download)
December 9-12, 2006
ASH

location:
Orlando, FL

Click here for the "ZIO-101, a Novel Organic Arsenic, Inhibits Human Myeloma Cell Growth in a SCID-hu Model" poster (1,190 KB Download)

Click here for the "Phase-1 Study of ZIO-101: a Novel Organic Arsenic Active in Acute Myelogenous Leukemia (AML) and Multiple Myeloma (MM)" poster (1,010 KB Download)
November 7-10, 2006
18th EORTC-NCI-AACR "Molecular Targets and Cancer Therapeutics"

location:
Prague, Czech Republic

Click here for the "ZIO-101: A New Organic Arsenic in Advanced Cancers, Determination of MTD and Preliminary Activity Data" poster (923 KB Download)

Click here for the "Organic and Inorganic Arsenics Operate by Different Biochemical Pathways to Induce Apoptosis in Cancer Cells" poster (974 KB Download)
November 2-4, 2006
CTOS

location:
Venice, Italy

Click here for the "Phase-1 Trials of ZIO-201 (Isophosphoramide Mustard-Lysine), (IPM): The Active Moiety of Ifosfamide: Potential Role in Sarcoma" poster (540 KB Download)

Click here for the "A Preclinical Evaluation Of ZIO-201 (ISOPHOSPHORAMIDE Mustard (IPM)-lysine) In Sarcoma" presentation (224 KB Download)
September 29 - October 3, 2006
ESMO

location:
Istanbul, Turkey

Click here for the "Safety and Activity of ZIO-101, A New Organic Arsenic, in Advanced Cancer" poster (702 KB Download)
September 14-16, 2006
ESH

location:
Madeira, Portugal

Click here for the "ZIO-101: A Novel Organic Arsenic Active in AML and MDS. Might it Work in MPD?" poster (480 KB Download)
June 2-6, 2006
ASCO

location:
Atlanta, GA

Click here for the "Phase - Study of Isophosphoramide Mustard (IPMP)-Lysine (ZIO-201) in advanced cancers" poster (628 KB Download)
April 1-5, 2006
AACR

location:
Washington, D.C.

Click here for the "Development and anti-cancer testing of halogenated analogues of Isophosphoramide Mustard-Lysine (IPM-L; ZIO-201), ZIO-202 & ZIO-203" poster (663 KB Download)
February 16-20, 2006
BMT Tandem Meetings

location:
Honolulu, HI

Click here for the "Isophosphoramide Mustard-Lysine (ZIO-201), A potential new alkylator for bone marrow transplants" poster (407 KB Download)
December 15-18, 2005
ASH

location:
Atlanta, GA

Click here for the "In Vitro Activity Of a Novel Organic Arsenical (S-Dimethylarsino-Glutathione, ZIO-101) Against Multiple Myeloma" abstract (39 KB Download)
November 14-18, 2005
AACR/NCI/EORTC

location:
Philadelphia, PA

Click here for the "A Novel Organic Arsenic Molecule: ZIO-101 (S-dimethylarsino-glutathione) Molecular Biology and Preliminary Results of a Phase-1 Study in Solid Malignancies" poster (495 KB Download)





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